Axial view of a selection of tissues segmented from MR Images of the head

Axial view of a selection of tissues segmented from MR Images of the head.





Overview - Database of Tissue Properties

With the material parameter database, IT’IS aims to provide the computational life sciences community with values for EM, thermal, fluid, acoustic and MR properties of biological tissues in a free, easily accessible, and dynamically evolving manner. The database is drawn from a comprehensive scientific literature review and is continuously updated. The IT’IS Foundation, a non-profit and independent research organization, is committed to the long-term maintenance of this material parameter database. IT'IS relies heavily on input from database users, whose engagement in the upkeep of the database via a specific forum is strongly encouraged.

With the SEMCAD X and Sim4Life simulation software packages, users are able to import the material database and automatically assign tissue parameter values to the Virtual Population models.

The database aims not only to provide the most up-to-date and comprehensive estimates for tissue material parameter values but also statistical information about the spread and standard deviation per tissue for the different thermal and fluidic parameters. This information is important for assessment of the contribution to the uncertainty in a quantity of interest due to the selection of the material parameters. For some material parameters, e.g., perfusion, the variation can be large, which in turn can have a server effect on simulation results.

The IT’IS material parameter database is envisioned as a webresource to be continuously developed and improved. General considerations, remarks, and known issues regarding the database are summarized in the documentation available for download. Although revised versions of the database have been published, previous versions remain accessible, together with a log file documenting the changes. Permanent digital access to each released version of the database and unambiguous traceability is guaranteed by a unique Digital Object Identifiers (DOI). Our user forum is designed for users to suggest additional references, to question the assumptions behind the current values, and to discuss possible improvements. The goal is to launch a community effort to create and maintain a comprehensive and accurate reference database for EM, thermal, flow, acoustic, and MR simulations involving human models. In the future, the material database will be extended to cover additional physical and physiological properties of tissues, including mechanical elasticity, and more.


Latest updates:

Recent improvements of the database include:

  • the publication of MR parameters (longitudinal and transversal relaxation times at 1.5 and 4 Tesla)
  • the publication of acoustic parameters (tissue speed of sound, tissue-dependent parameter of the non linearity parameter B/A, attenuation constant)
  • the publication of dynamic viscosity values at different temperatures  for various body fluids, including air, and the publication of temperature-dependent density, heat capacity, and thermal conductivity values for air
  • compatibility of the SEMCAD X automatic material-assignment tool with a wider range of models
  • conductivity values for frequencies lower than 120 Hz (Low Frequency Conductivity)
  • additional information regarding the dielectric properties
  • a log file that provides information about the changes in each release of the database.


How to reference our work:

Please use the following citation when referring to our database:

Hasgall PA, Di Gennaro F, Baumgartner C, Neufeld E, Gosselin MC, Payne D, Klingenböck A, Kuster N, “IT’IS Database for thermal and electromagnetic parameters of biological tissues,” Version 3.0, September 01st, 2015, DOI: 10.13099/VIP21000-03-0. www.itis.ethz.ch/database