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PUBLICATIONS

04/04/2017

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nk@itis.ethz.ch

 

A Radio Frequency Radiation Exposure System for Rodents Based on Reverberation Chambers

Myles H. Capstick, Sven Kuehn, Veronica Berdinas-Torres, Yijian Gong, Perry F. Wilson, John M. Ladbury, Galen Koepke, David L. McCormick, James Gauger, Ronald L. Melnick, and Niels Kuster, IEEE Transactions on Electromagnetic Compatibility, Volume 59, Issue 4, pp. 1041–1052. August 2017, online 17 March 2017, doi: 10.1109/TEMC.2017.2649885

 
PUBLICATIONS

28/03/2017

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nk@itis.ethz.ch

 

Computational hybrid anthropometric paediatric phantom library for internal radiation dosimetry

Tianwu Xie, Niels Kuster, and Habib Zaidi, Physics in Medicine and Biology, Volume 62, Issue 8, pp. 3263–3283. 21 April, 2017, online 28 March 2017, doi: 10.1088/1361-6560/aa63d0

 
PUBLICATIONS

13/03/2017

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nk@itis.ethz.ch

 

ELF‑MF exposure affects the robustness of epigenetic programming during granulopoiesis

Melissa Manser, Mohamad R. Abdul Sater, Christoph D. Schmid, Faiza Noreen, Manuel Murbach, Niels Kuster, David Schuermann, and Primo Schär, Scientific Reports 2017, Volume 7, Article number: 43345, online: 07 March 2017, DOI: 10.1038/srep43345. 

 
Evaluation of the potential of mobile phone specific electromagnetic fields (UMTS) to produce micronuclei in human glioblastoma cell lines
03/02/2017

Evaluation of the potential of mobile phone specific electromagnetic fields (UMTS) to produce micronuclei in human glioblastoma cell lines

Halh Al-Serori, Michael Kundi, Franziska Ferk, Miroslav Mišík, Armen Nersesyan, Manuel Murbach, Tamara T. Lah, and Siegfried Knasmüller. Toxicology In Vitro, Volume 40, pp. 264–271, April 2017, online 24 January 2017, DOI: 10.1016/j.tiv.

Recent epidemiological studies indicate that exposure to mobile-phone-specific electromagnetic fields (EMF) causes development of glioblastomas in humans. In this study, the effects of the universal mobile telecommunications system radiofrequency (UMTS-RF) signal – also known as 3G – on the formation of micronuclei (MN) due to structural and numerical chromosomal aberrations and other anomalies, such as nuclear buds (NB) that reflect gene amplification were assessed. Human glioblastoma cell lines, which were cultivated for 16 h in the presence and absence of fetal calf serum, were exposed to EMF with the well-characterized sXc1950 exposure system designed by the IT’IS Foundation. No evidence for induction of MN or other anomalies was found when the cells were exposed to EMF at specific absorption rate (SAR) levels of 0.25, 0.50, and 1.00 W/kg, which suggests that the UMTS-RF signal does not cause chromosomal damage in glioblastoma cells. However, at the highest exposure dose of 1.00 W/kg, morphological features observed in U251 cells indicate the induction of programmed cell death (apoptosis). The mechanisms that may lead to apoptosis induction will be investigated in follow-up studies.

The scientific and technical impact of the study can be summarized as:

    • The double-blinded exposure protocols of the sXc1950 system were used in RF exposure experiments on human glioblastoma cells to investigate possible RF mobile-phone-specific radiation effects on chromosomal stability.
    • No evidence was found for induction of MN formation or several other nuclear anomalies.
    • Induction of apoptosis was observed in a p53-mutated cell line (U251), while, in p53-proficient cells (U87), the apoptosis rate was not increased.
PUBLICATIONS

02/02/2017

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nk@itis.ethz.ch

 

Effects of personalised exposure on self-rated electromagnetic hypersensitivity and sensibility – A double-blind randomised controlled trial

 

Imke van Moorselaar, Pauline Slottje, Pia Heller, Rob van Strien, Hans Kromhout, Manuel Murbach, Niels Kuster, Roel Vermeulen, and Anke Huss, Environment International, Volume 99, pp. 255–262, February 2017, online 09 December 2016, doi: 10.1016/j.envint.2016.11.031.

 
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