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PUBLICATIONS

15/01/2017

Contact
nk@itis.ethz.ch

 

Terahertz reflectarrays and nonuniform metasurfaces

Daniel Headland, Tiaoming Niu, Eduardo Carrasco, Derek Abbott, Shruti Nirantar, Sharath Sriram, Madhu Bhaskaran, Christophe Fumeaux, and Withawat Withayachumnankul, IEEE J. Sel. Topics Quantum Electron., online 20 December 2016, DOI: 10.1109/JSTQE.2016.2640452

 
From Image-Based Modeling to the Modeling of Imaging with the Virtual Population
31/10/2016

From Image-Based Modeling to the Modeling of Imaging with the Virtual Population

Esra Neufeld, Bryn Lloyd, and Niels Kuster, in Simulation and Synthesis in Medical Imaging, Proceedings of the First International Workshop, SASHIMI 2016, Held in Conjunction with MICCAI 2016, Athens, Greece, October 21, 2016, Volume 9968 of the series Lecture Notes in Computer Science, pp. 45–54, online October, 2016

Image data has been used to create the Virtual Population models, a suite of highly detailed anatomical models (male/female, neonates/children/adults/elderly, average build/obese), which have been found to be useful for a wide range of computational life sciences applications. The models are at the core of the Sim4Life simulation platform. Different image modalities provide a wealth of information to enable model functionalization by facilitation of parameterization and animation of the anatomy, consideration of tissue inhomogeneity, imposition of realistic boundary conditions, and integration of dynamic physiological models. Closing the circle, these functionalized anatomical models have also been used to generate virtual image data, particularly by simulation of MRI scanning. Thus, image data can be produced under controlled conditions and with known base-anatomy for different pulse sequences. Virtual imaging has been used to study various imaging artefacts.

The scientific and technical impact of the publication can be summarized as: 

  • A variety of image modalities have been used to functionalize static anatomical models to provide, e.g., inhomogeneous tissue property distributions (e.g., CT-based acoustic skull properties, DTI-based electrical anisotropy of neural tissue), model dynamics such as 4D breathing motion, and realistic boundary conditions (e.g., for flow simulations)
  • Examples of image-based functionalization of models are manifold, ranging from model parameterization, stature morphing and realistic posing to the integration of physiological models (e.g., neuromorphology and electrophysiology for brain stimulation modeling)
  • Virtual anatomical models can be used with information about tissue properties and coupled multi-scale modeling of the in vivo electromagnetic fields and induced spin-dynamics generated by MRI coils to produce virtual MRI scans
  • Virtual image data can be produced under controlled conditions and with known base-anatomies for a variety of pulse sequences and can be used, e.g., to study image artifacts

 

PUBLICATIONS

14/10/2016

Contact
nk@itis.ethz.ch

 

Signaling by sulfur-containing molecules. Quantitative aspects.

Willem H. Koppenol and Patricia L. Bounds, Archives of Biochemistry and Biophysics, online September 23, 2016

 
PUBLICATIONS

12/10/2016

Contact
nk@itis.ethz.ch

 

Magnetic Nanoparticle-Induced Hyperthermia with Appropriate Payloads: Paul Ehrlich’s “Magic (Nano)bullet” for Cancer Theranostics?

Nilroy R. Datta, Sunil Krishnan, Daniel E. Speiser, Esra Neufeld, Niels Kuster, Stefan Bodis, and Heinrich Hofmann,
Cancer Treatment Reviews, Volume 50, pp. 217–227, online September 2016

 
PUBLICATIONS

10/10/2016

Contact
nk@itis.ethz.ch

 

Approach to Validate Simulation-Based Distribution Predictions Combining the Gamma-Method and Uncertainty Assessment: Application to Focused Ultrasound

Esra Neufeld, Adamos Kyriacou, Wolfgang Kainz, and Niels Kuster, Journal of Verification, Validation and Uncertainty Quantification, Volume 1, Issue 3, 031006, online September 2016

 
PUBLICATIONS

23/09/2016

Contact
nk@itis.ethz.ch

 

Virtual Population-Based Assessment of the Impact of 3 Tesla Radiofrequency Shimming and Thermoregulation on Safety and B1+ Uniformity

Manuel Murbach, Esra Neufeld, Eugenia Cabot, Earl Zastrow, Juan Córcoles, Wolfgang Kainz, and Niels Kuster, Magnetic Resonance in Medicine, Volume 76, Issue 3, pp. 986–997, September 2016; Early View, September 2015, online September 24, 2015

 
PUBLICATIONS

15/08/2016

Contact
nk@itis.ethz.ch

 

Parallel smoothing pressure correction solver for biomedical flow problems: convergence criteria, preconditioning, scalability

Kathrin Burckhardt, Dominik Szczerba, Esra Neufeld, Krishnamurthy Muralidhar, and Niels Kuster, Progress in Computational Fluid Dynamics, Volume 16, Issue 4, pp. 201–215, online August 10, 2016

 
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